Sir Ronald Ross and the Malarial Parasite Discovery of its Route - From Man to Mosquito and Back

Although the weather was sultry and warm, the boy shivered with high fever. Even a thick blanket was not adequate for his shivers. He was having these fevers for the last few days periodically. What he did not know was that within the next day he would go into a coma, and unless he was given quinine immediately, he might die. In the late nineteenth century, such malaria attacks were very common all over the tropical countries including several temperate ones, extending all the way up to Sweden and Canada. Around 1880 Alphonse Laveran had demonstrated convincingly that malaria was caused by parasites present in the blood, but the important question was 'How do the gelms get there?' The disease could not be prevented unless the route of infection was established!